Reduced concentrations of the B cell cytokine interleukin 38 are associated with cardiovascular disease risk in overweight subjects

The IL‐1 family member IL‐38 (IL1F10) suppresses inflammatory and autoimmune conditions. Here, we report that plasma concentrations of IL‐38 in 288 healthy Europeans correlate positively with circulating memory B cells and plasmablasts. IL‐38 correlated negatively with age (p = 0.02) and was stable...

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Detaylı Bibliyografya
Yayımlandı:Eur J Immunol
Asıl Yazarlar: de Graaf, Dennis M., Jaeger, Martin, van den Munckhof, Inge C. L., ter Horst, Rob, Schraa, Kiki, Zwaag, Jelle, Kox, Matthijs, Fujita, Mayumi, Yamauchi, Takeshi, Mercurio, Laura, Madonna, Stefania, Rutten, Joost H.W., de Graaf, Jacqueline, Riksen, Niels P., van de Veerdonk, Frank L., Netea, Mihai G., Joosten, Leo A.B., Dinarello, Charles A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2020
Konular:
Allergy and inflammation
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7983920/
https://ncbi.nlm.nih.gov/pubmed/33125159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201948390
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