Increased proteinase 3 and neutrophil elastase plasma concentrations are associated with non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes

INTRODUCTION: Non-alcoholic fatty liver disease (NAFLD) is becoming a major health problem worldwide. Inflammation plays an important role in disease pathogenesis and recent studies have shown a potential role for the neutrophil serine proteases (NSPs) proteinase-3 (PR3) and neutrophil elastase (NE)...

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Publicado no:Mol Med
Main Authors: Mirea, Andreea-Manuela, Toonen, Erik J. M., van den Munckhof, Inge, Munsterman, Isabelle D., Tjwa, Eric T. T. L., Jaeger, Martin, Oosting, Marije, Schraa, Kiki, Rutten, Joost H. W., van der Graaf, Marinette, Riksen, Niels P., de Graaf, Jacqueline, Netea, Mihai G., Tack, Cees J., Chavakis, Triantafyllos, Joosten, Leo A. B.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6498541/
https://ncbi.nlm.nih.gov/pubmed/31046673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10020-019-0084-3
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