Increased proteinase 3 and neutrophil elastase plasma concentrations are associated with non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes

INTRODUCTION: Non-alcoholic fatty liver disease (NAFLD) is becoming a major health problem worldwide. Inflammation plays an important role in disease pathogenesis and recent studies have shown a potential role for the neutrophil serine proteases (NSPs) proteinase-3 (PR3) and neutrophil elastase (NE)...

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Publicat a:Mol Med
Autors principals: Mirea, Andreea-Manuela, Toonen, Erik J. M., van den Munckhof, Inge, Munsterman, Isabelle D., Tjwa, Eric T. T. L., Jaeger, Martin, Oosting, Marije, Schraa, Kiki, Rutten, Joost H. W., van der Graaf, Marinette, Riksen, Niels P., de Graaf, Jacqueline, Netea, Mihai G., Tack, Cees J., Chavakis, Triantafyllos, Joosten, Leo A. B.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6498541/
https://ncbi.nlm.nih.gov/pubmed/31046673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10020-019-0084-3
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