COVID-19 genetic risk variants are associated with expression of multiple genes in diverse immune cell types.

Common genetic polymorphisms associated with severity of COVID-19 illness can be utilized for discovering molecular pathways and cell types driving disease pathogenesis. Here, we assessed the effects of 679 COVID-19-risk variants on gene expression in a wide-range of immune cell types. Severe COVID-...

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Publicat a:bioRxiv
Autors principals: Schmiedel, Benjamin J., Chandra, Vivek, Rocha, Job, Gonzalez-Colin, Cristian, Bhattacharyya, Sourya, Madrigal, Ariel, Ottensmeier, Christian H., Ay, Ferhat, Vijayanand, Pandurangan
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7724655/
https://ncbi.nlm.nih.gov/pubmed/33299987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.12.01.407429
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