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Identifying statistically significant chromatin contacts from Hi-C data with FitHiC2

Fit-Hi-C is a programming application to compute statistical confidence estimates for Hi-C contact maps to identify significant chromatin contacts. By fitting a monotonically non-increasing spline, Fit-Hi-C captures the relationship between genomic distance and contact probability without any parame...

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Bibliografiske detaljer
Udgivet i:Nat Protoc
Main Authors: Kaul, Arya, Bhattacharyya, Sourya, Ay, Ferhat
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7451401/
https://ncbi.nlm.nih.gov/pubmed/31980751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41596-019-0273-0
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