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Statistical confidence estimation for Hi-C data reveals regulatory chromatin contacts
Our current understanding of how DNA is packed in the nucleus is most accurate at the fine scale of individual nucleosomes and at the large scale of chromosome territories. However, accurate modeling of DNA architecture at the intermediate scale of ∼50 kb–10 Mb is crucial for identifying functional...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4032863/ https://ncbi.nlm.nih.gov/pubmed/24501021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.160374.113 |
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