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Statistical confidence estimation for Hi-C data reveals regulatory chromatin contacts

Our current understanding of how DNA is packed in the nucleus is most accurate at the fine scale of individual nucleosomes and at the large scale of chromosome territories. However, accurate modeling of DNA architecture at the intermediate scale of ∼50 kb–10 Mb is crucial for identifying functional...

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Autori principali: Ay, Ferhat, Bailey, Timothy L., Noble, William Stafford
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032863/
https://ncbi.nlm.nih.gov/pubmed/24501021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.160374.113
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