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Statistical confidence estimation for Hi-C data reveals regulatory chromatin contacts

Our current understanding of how DNA is packed in the nucleus is most accurate at the fine scale of individual nucleosomes and at the large scale of chromosome territories. However, accurate modeling of DNA architecture at the intermediate scale of ∼50 kb–10 Mb is crucial for identifying functional...

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Detalles Bibliográficos
Main Authors: Ay, Ferhat, Bailey, Timothy L., Noble, William Stafford
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032863/
https://ncbi.nlm.nih.gov/pubmed/24501021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.160374.113
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