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Identification of significant chromatin contacts from HiChIP data by FitHiChIP
HiChIP/PLAC-seq is increasingly becoming popular for profiling 3D chromatin contacts among regulatory elements and for annotating functions of genetic variants. Here we describe FitHiChIP, a computational method for loop calling from HiChIP/PLAC-seq data, which jointly models the non-uniform coverag...
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| Опубликовано в: : | Nat Commun |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6748947/ https://ncbi.nlm.nih.gov/pubmed/31530818 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11950-y |
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