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Identification of significant chromatin contacts from HiChIP data by FitHiChIP

HiChIP/PLAC-seq is increasingly becoming popular for profiling 3D chromatin contacts among regulatory elements and for annotating functions of genetic variants. Here we describe FitHiChIP, a computational method for loop calling from HiChIP/PLAC-seq data, which jointly models the non-uniform coverag...

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Vydáno v:Nat Commun
Hlavní autoři: Bhattacharyya, Sourya, Chandra, Vivek, Vijayanand, Pandurangan, Ay, Ferhat
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748947/
https://ncbi.nlm.nih.gov/pubmed/31530818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11950-y
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