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Parkin interacts with Mitofilin to increase dopaminergic neuron death in response to Parkinson’s disease-related stressors
Mitochondrial dysfunction plays a critical role in the pathophysiology of Parkinson’s disease (PD). The inner mitochondrial membrane (IMM) protein, Mitofilin or Mic60, has been shown to play a key role in controlling and maintaining mitochondrial cristae morphology, and its dysregulation induces cyt...
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| Pubblicato in: | Am J Transl Res |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
e-Century Publishing Corporation
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7724356/ https://ncbi.nlm.nih.gov/pubmed/33312388 |
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