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Inner mitochondrial membrane protein MPV17 mutant mice display increased myocardial injury after ischemia/reperfusion

MPV17 is an inner mitochondrial membrane protein whose mutation results in mitochondrial DNA (mtDNA) depletion diseases such as neurohepatopathy. MPV17 is expressed in several organs including the liver and kidneys. Here, we investigated its role and mechanism of action in cardiac ischemia/reperfusi...

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Bibliographic Details
Published in:Am J Transl Res
Main Authors: Madungwe, Ngonidzashe B, Feng, Yansheng, Imam Aliagan, Abdulhafiz, Tombo, Nathalie, Kaya, Ferdinand, Bopassa, Jean C
Format: Artigo
Language:Inglês
Published: e-Century Publishing Corporation 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7407695/
https://ncbi.nlm.nih.gov/pubmed/32774709
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