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Parkin interacts with Mitofilin to increase dopaminergic neuron death in response to Parkinson’s disease-related stressors

Mitochondrial dysfunction plays a critical role in the pathophysiology of Parkinson’s disease (PD). The inner mitochondrial membrane (IMM) protein, Mitofilin or Mic60, has been shown to play a key role in controlling and maintaining mitochondrial cristae morphology, and its dysregulation induces cyt...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Imam Aliagan, Abdulhafiz D, Ahwazi, Mina D, Tombo, Nathalie, Feng, Yansheng, Bopassa, Jean C
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7724356/
https://ncbi.nlm.nih.gov/pubmed/33312388
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