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Base editing: advances and therapeutic opportunities

Base editing — the introduction of single-nucleotide variants (SNVs) into DNA or RNA in living cells — is one of the most recent advances in the field of genome editing. As around half of known pathogenic genetic variants are due to SNVs, base editing holds great potential for the treatment of numer...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Rev Drug Discov
Egile Nagusiak: Porto, Elizabeth M., Komor, Alexis C., Slaymaker, Ian M., Yeo, Gene W.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7721651/
https://ncbi.nlm.nih.gov/pubmed/33077937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41573-020-0084-6
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