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Base editing: advances and therapeutic opportunities
Base editing — the introduction of single-nucleotide variants (SNVs) into DNA or RNA in living cells — is one of the most recent advances in the field of genome editing. As around half of known pathogenic genetic variants are due to SNVs, base editing holds great potential for the treatment of numer...
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| Vydáno v: | Nat Rev Drug Discov |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7721651/ https://ncbi.nlm.nih.gov/pubmed/33077937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41573-020-0084-6 |
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