Structural basis for polarized elongation of actin filaments

Actin filaments elongate and shorten much faster at their barbed end than their pointed end, but the molecular basis of this difference has not been understood. We use all-atom molecular dynamics simulations to investigate the properties of subunits at both ends of the filament. The terminal subunit...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Zsolnay, Vilmos, Katkar, Harshwardhan H., Chou, Steven Z., Pollard, Thomas D., Voth, Gregory A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2020
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7720195/
https://ncbi.nlm.nih.gov/pubmed/33199648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2011128117
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