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Structural basis for polarized elongation of actin filaments

Actin filaments elongate and shorten much faster at their barbed end than their pointed end, but the molecular basis of this difference has not been understood. We use all-atom molecular dynamics simulations to investigate the properties of subunits at both ends of the filament. The terminal subunit...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Zsolnay, Vilmos, Katkar, Harshwardhan H., Chou, Steven Z., Pollard, Thomas D., Voth, Gregory A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7720195/
https://ncbi.nlm.nih.gov/pubmed/33199648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2011128117
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