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Structural basis for polarized elongation of actin filaments

Actin filaments elongate and shorten much faster at their barbed end than their pointed end, but the molecular basis of this difference has not been understood. We use all-atom molecular dynamics simulations to investigate the properties of subunits at both ends of the filament. The terminal subunit...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Zsolnay, Vilmos, Katkar, Harshwardhan H., Chou, Steven Z., Pollard, Thomas D., Voth, Gregory A.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7720195/
https://ncbi.nlm.nih.gov/pubmed/33199648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2011128117
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