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Markov state modeling reveals alternative unbinding pathways for peptide–MHC complexes
Peptide binding to major histocompatibility complexes (MHCs) is a central component of the immune system, and understanding the mechanism behind stable peptide–MHC binding will aid the development of immunotherapies. While MHC binding is mostly influenced by the identity of the so-called anchor posi...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7720115/ https://ncbi.nlm.nih.gov/pubmed/33184174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2007246117 |
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