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Markov state modeling reveals alternative unbinding pathways for peptide–MHC complexes
Peptide binding to major histocompatibility complexes (MHCs) is a central component of the immune system, and understanding the mechanism behind stable peptide–MHC binding will aid the development of immunotherapies. While MHC binding is mostly influenced by the identity of the so-called anchor posi...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7720115/ https://ncbi.nlm.nih.gov/pubmed/33184174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2007246117 |
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