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Large-Scale Structure-Based Prediction of Stable Peptide Binding to Class I HLAs Using Random Forests

Prediction of stable peptide binding to Class I HLAs is an important component for designing immunotherapies. While the best performing predictors are based on machine learning algorithms trained on peptide-HLA (pHLA) sequences, the use of structure for training predictors deserves further explorati...

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Pubblicato in:Front Immunol
Autori principali: Abella, Jayvee R., Antunes, Dinler A., Clementi, Cecilia, Kavraki, Lydia E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7387700/
https://ncbi.nlm.nih.gov/pubmed/32793224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01583
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