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Large-Scale Structure-Based Prediction of Stable Peptide Binding to Class I HLAs Using Random Forests

Prediction of stable peptide binding to Class I HLAs is an important component for designing immunotherapies. While the best performing predictors are based on machine learning algorithms trained on peptide-HLA (pHLA) sequences, the use of structure for training predictors deserves further explorati...

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Publicat a:Front Immunol
Autors principals: Abella, Jayvee R., Antunes, Dinler A., Clementi, Cecilia, Kavraki, Lydia E.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7387700/
https://ncbi.nlm.nih.gov/pubmed/32793224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01583
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