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Assessment of hepatic pyruvate carboxylase activity using hyperpolarized [1-(13)C]-L-lactate
PURPOSE: To evaluate the utility of hyperpolarized [1-(13)C]-L-lactate to detect hepatic pyruvate carboxylase (PC) activity in vivo under fed and fasted conditions. METHODS: [1-(13)C]-labeled sodium L-lactate was polarized using a SPINlab polarizer. Polarization level and the T(1) were measured in v...
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| Publicado no: | Magn Reson Med |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7718288/ https://ncbi.nlm.nih.gov/pubmed/32936474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.28489 |
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