MBCL-21. GERMLINE ELONGATOR MUTATIONS IN SONIC HEDGEHOG MEDULLOBLASTOMA

BACKGROUND: Our previous analysis of established cancer predisposition genes in medulloblastoma (MB) identified pathogenic germline variants in ~5% of all patients. Here, we extended our analysis to include all protein-coding genes. METHODS: Case-control analysis performed on 795 MB patients against...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Robinson, Giles W, Waszak, Sebastian M, Gudenas, Brian L, Smith, Kyle S, Forget, Antoine, Kojic, Marija, Jesus, Garcia-Lopez, Hadley, Jennifer, Hamilton, Kayla V, Indersie, Emilie, Buchhalter, Ivo, Jager, Natalie, Sharma, Tanvi, Rausch, Tobias, Kool, Marcel, Sturm, Dominic, Jones, David T W, Tatevossian, Ruth, Lombard, Berangere, Loew, Damarys, Bowers, Daniel, Bendel, Anne, Partap, Sonia, Chintagumpala, Murali, Crawford, John, Gottardo, Nicholas G, Smith, Amy, Dufour, Christelle, Rutkowski, Stefan, Grotzer, Michael, Remke, Mark, Puget, Stephanie, Pajtler, Kristian W, Milde, Till, Witt, Olaf, Ryzhova, Marina, Korshunov, Andrey, Orr, Brent A, Ellison, David W, Brugieres, Laurence, Lichter, Peter, Nichols, Kim E, Gajjar, Amar, Wainwright, Brandon J, Ayrault, Olivier, Korbel, Jan O, Northcott, Paul A, Pfister, Stefan M
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
Medulloblastoma (Clinical)
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715847/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.497
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