MBCL-21. GERMLINE ELONGATOR MUTATIONS IN SONIC HEDGEHOG MEDULLOBLASTOMA

BACKGROUND: Our previous analysis of established cancer predisposition genes in medulloblastoma (MB) identified pathogenic germline variants in ~5% of all patients. Here, we extended our analysis to include all protein-coding genes. METHODS: Case-control analysis performed on 795 MB patients against...

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Vydáno v:Neuro Oncol
Hlavní autoři: Robinson, Giles W, Waszak, Sebastian M, Gudenas, Brian L, Smith, Kyle S, Forget, Antoine, Kojic, Marija, Jesus, Garcia-Lopez, Hadley, Jennifer, Hamilton, Kayla V, Indersie, Emilie, Buchhalter, Ivo, Jager, Natalie, Sharma, Tanvi, Rausch, Tobias, Kool, Marcel, Sturm, Dominic, Jones, David T W, Tatevossian, Ruth, Lombard, Berangere, Loew, Damarys, Bowers, Daniel, Bendel, Anne, Partap, Sonia, Chintagumpala, Murali, Crawford, John, Gottardo, Nicholas G, Smith, Amy, Dufour, Christelle, Rutkowski, Stefan, Grotzer, Michael, Remke, Mark, Puget, Stephanie, Pajtler, Kristian W, Milde, Till, Witt, Olaf, Ryzhova, Marina, Korshunov, Andrey, Orr, Brent A, Ellison, David W, Brugieres, Laurence, Lichter, Peter, Nichols, Kim E, Gajjar, Amar, Wainwright, Brandon J, Ayrault, Olivier, Korbel, Jan O, Northcott, Paul A, Pfister, Stefan M
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Medulloblastoma (Clinical)
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715847/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.497
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