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DIPG-82. CLINICAL EXPERIENCE OF CONVECTION ENHANCED DELIVERY (CED) OF CARBOPLATIN AND SODIUM VALPROATE INTO THE PONS FOR THE TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) IN CHILDREN AND YOUNG ADULTS AFTER RADIOTHERAPY

PURPOSE: Effective treatment of diffuse intrinsic pontine glioma (DIPG) remains a formidable challenge due to inadequate penetration of the blood-brain barrier (BBB) by systemically administered chemotherapies. The BBB can be overcome by directly infusing drugs into pons using method of convection-e...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Szychot, Elwira, Walker, David, Collins, Peter, Hyare, Harpreet, Shankar, Ananth, Bienemann, Alison, Hollingworth, Milo, Gill, Steven
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715416/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.123
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