DIPG-82. CLINICAL EXPERIENCE OF CONVECTION ENHANCED DELIVERY (CED) OF CARBOPLATIN AND SODIUM VALPROATE INTO THE PONS FOR THE TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) IN CHILDREN AND YOUNG ADULTS AFTER RADIOTHERAPY

PURPOSE: Effective treatment of diffuse intrinsic pontine glioma (DIPG) remains a formidable challenge due to inadequate penetration of the blood-brain barrier (BBB) by systemically administered chemotherapies. The BBB can be overcome by directly infusing drugs into pons using method of convection-e...

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Publicado en:Neuro Oncol
Autores principales: Szychot, Elwira, Walker, David, Collins, Peter, Hyare, Harpreet, Shankar, Ananth, Bienemann, Alison, Hollingworth, Milo, Gill, Steven
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2020
Materias:
Diffuse Midline Glioma/DIPG
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715416/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.123
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