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DIPG-82. CLINICAL EXPERIENCE OF CONVECTION ENHANCED DELIVERY (CED) OF CARBOPLATIN AND SODIUM VALPROATE INTO THE PONS FOR THE TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) IN CHILDREN AND YOUNG ADULTS AFTER RADIOTHERAPY

PURPOSE: Effective treatment of diffuse intrinsic pontine glioma (DIPG) remains a formidable challenge due to inadequate penetration of the blood-brain barrier (BBB) by systemically administered chemotherapies. The BBB can be overcome by directly infusing drugs into pons using method of convection-e...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Szychot, Elwira, Walker, David, Collins, Peter, Hyare, Harpreet, Shankar, Ananth, Bienemann, Alison, Hollingworth, Milo, Gill, Steven
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715416/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.123
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