DIPG-40. TARGETING MASTER REGULATOR DEPENDENCIES IN DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)

Diffuse intrinsic pontine glioma (DIPG) remains a fatal disease with no effective drugs to date. Mutation-based precision oncology approaches are limited by lack of targetable mutations and genetic heterogeneity. We leveraged systems biology methodologies to discover common targetable disease driver...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Pavisic, Jovana, Sethi, Chankrit, Jones, Chris, Zacharoulis, Stergios, Califano, Andrea
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
Diffuse Midline Glioma/DIPG
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715415/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.087
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