DIPG-59. UPREGULATION OF PRENATAL PONTINE ID1 SIGNALING IN DIPG

BACKGROUND: Diffuse intrinsic pontine gliomas (DIPGs) are lethal pediatric brain tumors with no curative therapies. Inhibitor of DNA binding (ID) proteins are key regulators of gene differentiation during embryogenesis. Previous work has shown that H3F3A and ACVR1 mutations increase ID1 expression i...

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Publicado en:Neuro Oncol
Autores principales: Harris, Micah K, Yadav, Viveka Nand, Stallard, Stefanie, Woo, Rinette, Siddaway, Robert, Qin, Tingting, Mullan, Brendan, Miklja, Zachary, Siada, Ruby, Ravindran, Ramya, Cao, Xuhong, Pasternak, Amy, Castro, Maria G, Lowenstein, Pedro R, Mody, Rajen, Chinnaiyan, Arul, Hawkins, Cynthia, Desprez, Pierre, McAllister, Sean, Venneti, Sriram, Koschmann, Carl
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2020
Materias:
Diffuse Midline Glioma/DIPG
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715087/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.104
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