DIPG-59. UPREGULATION OF PRENATAL PONTINE ID1 SIGNALING IN DIPG

BACKGROUND: Diffuse intrinsic pontine gliomas (DIPGs) are lethal pediatric brain tumors with no curative therapies. Inhibitor of DNA binding (ID) proteins are key regulators of gene differentiation during embryogenesis. Previous work has shown that H3F3A and ACVR1 mutations increase ID1 expression i...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Harris, Micah K, Yadav, Viveka Nand, Stallard, Stefanie, Woo, Rinette, Siddaway, Robert, Qin, Tingting, Mullan, Brendan, Miklja, Zachary, Siada, Ruby, Ravindran, Ramya, Cao, Xuhong, Pasternak, Amy, Castro, Maria G, Lowenstein, Pedro R, Mody, Rajen, Chinnaiyan, Arul, Hawkins, Cynthia, Desprez, Pierre, McAllister, Sean, Venneti, Sriram, Koschmann, Carl
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Diffuse Midline Glioma/DIPG
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715087/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.104
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