DIPG-59. UPREGULATION OF PRENATAL PONTINE ID1 SIGNALING IN DIPG

BACKGROUND: Diffuse intrinsic pontine gliomas (DIPGs) are lethal pediatric brain tumors with no curative therapies. Inhibitor of DNA binding (ID) proteins are key regulators of gene differentiation during embryogenesis. Previous work has shown that H3F3A and ACVR1 mutations increase ID1 expression i...

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Библиографические подробности
Опубликовано в: :Neuro Oncol
Главные авторы: Harris, Micah K, Yadav, Viveka Nand, Stallard, Stefanie, Woo, Rinette, Siddaway, Robert, Qin, Tingting, Mullan, Brendan, Miklja, Zachary, Siada, Ruby, Ravindran, Ramya, Cao, Xuhong, Pasternak, Amy, Castro, Maria G, Lowenstein, Pedro R, Mody, Rajen, Chinnaiyan, Arul, Hawkins, Cynthia, Desprez, Pierre, McAllister, Sean, Venneti, Sriram, Koschmann, Carl
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2020
Предметы:
Diffuse Midline Glioma/DIPG
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715087/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.104
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