DIPG-34. SUPER ELONGATION COMPLEX AS A TARGETABLE DEPENDENCY IN H3K27M+ DIFFUSE MIDLINE GLIOMA

Mutations in the histone 3 gene (H3K27M) are the eponymous driver in diffuse intrinsic pontine gliomas (DIPGs) and other diffuse midline gliomas (DMGs), aggressive pediatric brain tumors for which no curative therapy currently exists. To identify specific epigenetic dependencies within the context o...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neuro Oncol
Prif Awduron: Dahl, Nathan, Danis, Etienne, Balakrishnan, Ilango, Wang, Dong, Pierce, Angela, Walker, Faye, Gilani, Ahmed, Serkova, Natalie, Madhaven, Krishna, Fosmire, Susan, Green, Adam, Foreman, Nicholas, Venkataraman, Sujatha, Vibhakar, Rajeev
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2020
Pynciau:
Diffuse Midline Glioma/DIPG
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715266/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.082
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