DIPG-34. SUPER ELONGATION COMPLEX AS A TARGETABLE DEPENDENCY IN H3K27M+ DIFFUSE MIDLINE GLIOMA

Mutations in the histone 3 gene (H3K27M) are the eponymous driver in diffuse intrinsic pontine gliomas (DIPGs) and other diffuse midline gliomas (DMGs), aggressive pediatric brain tumors for which no curative therapy currently exists. To identify specific epigenetic dependencies within the context o...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Neuro Oncol
Egile Nagusiak: Dahl, Nathan, Danis, Etienne, Balakrishnan, Ilango, Wang, Dong, Pierce, Angela, Walker, Faye, Gilani, Ahmed, Serkova, Natalie, Madhaven, Krishna, Fosmire, Susan, Green, Adam, Foreman, Nicholas, Venkataraman, Sujatha, Vibhakar, Rajeev
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2020
Gaiak:
Diffuse Midline Glioma/DIPG
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715266/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.082
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