DIPG-10. THE ONCOGENIC ROLE OF THE SUPER ELONGATION COMPLEX IN H3K27M-MUTANT DIFFUSE MIDLINE GLIOMAS

Mutations in the histone 3 (H3) gene (H3K27M) are the eponymous driver in diffuse midline gliomas (DMGs). Emerging understanding of H3K27M biology suggests that secondary cooperating factors are required to promote oncogenesis. We have identified AFF4, a component of the super elongation complex (SE...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Neuro Oncol
Hauptverfasser: Dahl, Nathan A, Venkataraman, Sujatha, Balakrishnan, Ilango, Madhavan, Krishna, Fosmire, Susan, Vibhakar, Rajeev
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
Schlagworte:
Abstracts
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012884/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.103
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge