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DIPG-76. HISTONE H3 PHOSPHORYLATION IN H3K27M MIDLINE GLIOMAS

Diffuse midline gliomas (DMG) patients have a dire prognosis despite radiation therapy and there is an urgent need to develop more effective treatments. DMG are characterized by heterozygous mutations in select H3 genes resulting in the replacement of lysine 27 by methionine (K27M) that leads to glo...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Zhang, Liang, Day, Charles, Hinchcliffe, Edward, Daniels, David
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715133/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.118
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