DIPG-47. HISTONE MUTATIONS ENHANCE RAS MEDIATED ERK5 GROWTH SIGNALING IN DIFFUSE MIDLINE GLIOMAS

Diffuse midline gliomas (DMGs) are incurable brain tumors with an aggressive onset. Apart from irradiation, there are currently no effective therapies available for patients with DMG, who have a median survival time of less than one year. Most DMG cells harbor mutations in genes encoding histone H3...

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Vydáno v:Neuro Oncol
Hlavní autoři: Stanton, Ann-Catherine, Koncar, Robert, Golbourn, Brian, Dey, Brittany, Agrawal, Nishant, Mack, Stephen, Pollack, Ian, Agnihotri, Sameer
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Diffuse Midline Glioma/DIPG
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715289/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.093
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