DIPG-58. HISTONE H3 WILD-TYPE DIPG/DMG OVEREXPRESSING EZHIP EXTEND THE SPECTRUM OF DIFFUSE MIDLINE GLIOMAS WITH PRC2 INHIBITION BEYOND H3-K27M MUTATION

Diffuse midline gliomas (DMG) H3 K27M-mutant were introduced in the 2016 WHO Classification unifying diffuse intrinsic pontine gliomas (DIPG) and gliomas from the thalamus and spinal cord harboring a histone H3-K27M mutation leading to Polycomb Repressor Complex 2 (PRC2) inhibition. However, few cas...

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Vydáno v:Neuro Oncol
Hlavní autoři: Castel, David, Kergrohen, Thomas, Tauziède-Espariat, Arnault, Mackay, Alan, Ghermaoui, Samia, Lechapt, Emmanuèle, Pfister, Stefan, Kramm, Christof, Boddaert, Nathalie, Blauwblomme, Thomas, Puget, Stéphanie, Beccaria, Kévin, Jones, Chris, Jones, David, Varlet, Pascale, Grill, Jacques, Debily, Marie-Anne
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Diffuse Midline Glioma/DIPG
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715950/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.103
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