Alpha 1 Antitrypsin-Deficient Macrophages Have Impaired Efferocytosis of Apoptotic Neutrophils

Alpha 1 antitrypsin deficiency (AATD) is an autosomal co-dominant disorder characterized by a low level of circulating AAT, which significantly reduces protection for the lower airways against proteolytic burden caused by neutrophils. Neutrophils, which are terminally differentiated innate immune ce...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Lee, Jungnam, Lu, Yuanqing, Oshins, Regina, West, Jesse, Moneypenny, Craig G., Han, Kyudong, Brantly, Mark L.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7714766/
https://ncbi.nlm.nih.gov/pubmed/33329539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.574410
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