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Neutrophil elastase promotes macrophage cell adhesion and cytokine production through the integrin-Src kinases pathway

There are a number of respiratory diseases characterized by the presence of excess neutrophil elastase (NE) activity in tissues, including cystic fibrosis and chronic obstructive pulmonary disease (COPD). NE is considered a primary contributor to disease development, but the precise mechanism has ye...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Krotova, Karina, Khodayari, Nazli, Oshins, Regina, Aslanidi, George, Brantly, Mark L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7522083/
https://ncbi.nlm.nih.gov/pubmed/32981934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-72667-3
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