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S. aureus blocks efferocytosis of neutrophils by macrophages through the activity of its virulence factor alpha toxin

Bacterial pneumonia, such as those caused by Staphylococcus aureus, is associated with an influx of inflammatory neutrophils into the lung tissue and airways. Regulation and clearance of recruited neutrophils is essential for preventing tissue damage by “friendly fire”, a responsibility of macrophag...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Cohen, Taylor S., Jones-Nelson, Omari, Hotz, Meghan, Cheng, Lily, Miller, Lloyd S., Suzich, JoAnn, Stover, C. Kendall, Sellman, Bret R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5064327/
https://ncbi.nlm.nih.gov/pubmed/27739519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35466
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