Neutralizing Alpha-Toxin Accelerates Healing of Staphylococcus aureus-Infected Wounds in Nondiabetic and Diabetic Mice

Staphylococcus aureus wound infections delay healing and result in invasive complications such as osteomyelitis, especially in the setting of diabetic foot ulcers. In preclinical animal models of S. aureus skin infection, antibody neutralization of alpha-toxin (AT), an S. aureus-secreted pore-formin...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Ortines, Roger V., Liu, Haiyun, Cheng, Lily I., Cohen, Taylor S., Lawlor, Heather, Gami, Abhishek, Wang, Yu, Dillen, Carly A., Archer, Nathan K., Miller, Robert J., Ashbaugh, Alyssa G., Pinsker, Bret L., Marchitto, Mark C., Tkaczyk, Christine, Stover, C. Kendall, Sellman, Bret R., Miller, Lloyd S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826123/
https://ncbi.nlm.nih.gov/pubmed/29311091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02288-17
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