Efficacy of a Multimechanistic Monoclonal Antibody Combination against Staphylococcus aureus Surgical Site Infections in Mice

Surgical site infections (SSIs) are commonly caused by Staphylococcus aureus. We report that a combination of three monoclonal antibodies (MEDI6389) that neutralize S. aureus alpha-toxin, clumping factor A, and four leukocidins (LukSF, LukED, HlgAB, and HlgCB) plus vancomycin had enhanced efficacy c...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Ortines, Roger V., Wang, Yu, Liu, Haiyun, Dikeman, Dustin A., Pinsker, Bret L., Miller, Robert J., Kim, Sophia E., Ackerman, Nicole E., Rizkallah, Joe F., Marcello, LeeAnn T., Cohen, Taylor S., Tkaczyk, Christine, Sellman, Bret R., Miller, Lloyd S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6658795/
https://ncbi.nlm.nih.gov/pubmed/31138566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00346-19
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados