Critical Role of Alpha-Toxin and Protective Effects of Its Neutralization by a Human Antibody in Acute Bacterial Skin and Skin Structure Infections

Methicillin-resistant Staphylococcus aureus (MRSA) causes large-scale epidemics of acute bacterial skin and skin structure infections (ABSSSI) within communities across the United States. Animal models that reproduce ABSSSI as they occur in humans are urgently needed to test new therapeutic strategi...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Le, Vien T. M., Tkaczyk, Christine, Chau, Sally, Rao, Renee L., Dip, Etyene Castro, Pereira-Franchi, Eliane P., Cheng, Lily, Lee, Sally, Koelkebeck, Holly, Hilliard, Jamese J., Yu, Xiang Qing, Datta, Vivekananda, Nguyen, Vien, Weiss, William, Prokai, Laszlo, O'Day, Terrence, Stover, C. Kendall, Sellman, Bret R., Diep, Binh An
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2016
Soggetti:
Experimental Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5038308/
https://ncbi.nlm.nih.gov/pubmed/27401576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00710-16
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