Critical Role of Alpha-Toxin and Protective Effects of Its Neutralization by a Human Antibody in Acute Bacterial Skin and Skin Structure Infections

Methicillin-resistant Staphylococcus aureus (MRSA) causes large-scale epidemics of acute bacterial skin and skin structure infections (ABSSSI) within communities across the United States. Animal models that reproduce ABSSSI as they occur in humans are urgently needed to test new therapeutic strategi...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Le, Vien T. M., Tkaczyk, Christine, Chau, Sally, Rao, Renee L., Dip, Etyene Castro, Pereira-Franchi, Eliane P., Cheng, Lily, Lee, Sally, Koelkebeck, Holly, Hilliard, Jamese J., Yu, Xiang Qing, Datta, Vivekananda, Nguyen, Vien, Weiss, William, Prokai, Laszlo, O'Day, Terrence, Stover, C. Kendall, Sellman, Bret R., Diep, Binh An
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2016
Materias:
Experimental Therapeutics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5038308/
https://ncbi.nlm.nih.gov/pubmed/27401576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00710-16
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