Critical Role of Alpha-Toxin and Protective Effects of Its Neutralization by a Human Antibody in Acute Bacterial Skin and Skin Structure Infections

Methicillin-resistant Staphylococcus aureus (MRSA) causes large-scale epidemics of acute bacterial skin and skin structure infections (ABSSSI) within communities across the United States. Animal models that reproduce ABSSSI as they occur in humans are urgently needed to test new therapeutic strategi...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Le, Vien T. M., Tkaczyk, Christine, Chau, Sally, Rao, Renee L., Dip, Etyene Castro, Pereira-Franchi, Eliane P., Cheng, Lily, Lee, Sally, Koelkebeck, Holly, Hilliard, Jamese J., Yu, Xiang Qing, Datta, Vivekananda, Nguyen, Vien, Weiss, William, Prokai, Laszlo, O'Day, Terrence, Stover, C. Kendall, Sellman, Bret R., Diep, Binh An
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2016
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5038308/
https://ncbi.nlm.nih.gov/pubmed/27401576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00710-16
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