Targeting Alpha Toxin To Mitigate Its Lethal Toxicity in Ferret and Rabbit Models of Staphylococcus aureus Necrotizing Pneumonia

The role broad-spectrum antibiotics play in the spread of antimicrobial resistance, coupled with their effect on the healthy microbiome, has led to advances in pathogen-specific approaches for the prevention or treatment of serious bacterial infections. One approach in clinical testing is passive im...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Main Authors: Diep, Binh An, Hilliard, Jamese J., Le, Vien T. M., Tkaczyk, Christine, Le, Hoan N., Tran, Vuvi G., Rao, Renee L., Dip, Etyene Castro, Pereira-Franchi, Eliane P., Cha, Paulyn, Jacobson, Scott, Broome, Rosemary, Cheng, Lily I., Weiss, William, Prokai, Laszlo, Nguyen, Vien, Stover, C. Ken, Sellman, Bret R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2017
Assuntos:
Experimental Therapeutics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5365647/
https://ncbi.nlm.nih.gov/pubmed/28115346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02456-16
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