Effects of Linezolid on Suppressing In Vivo Production of Staphylococcal Toxins and Improving Survival Outcomes in a Rabbit Model of Methicillin-Resistant Staphylococcus aureus Necrotizing Pneumonia

Background. Linezolid is recommended for treatment of pneumonia and other invasive infections caused by methicillin-resistant Staphylococcus aureus (MRSA). The premise underlying this recommendation is that linezolid inhibits in vivo production of potent staphylococcal exotoxins, including Panton-Va...

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Detalhes bibliográficos
Main Authors: Diep, Binh An, Afasizheva, Anna, Le, Hoan N., Kajikawa, Osamu, Matute-Bello, Gustavo, Tkaczyk, Christine, Sellman, Bret, Badiou, Cedric, Lina, Gerard, Chambers, Henry F.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666136/
https://ncbi.nlm.nih.gov/pubmed/23532096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jit129
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