Effects of Tedizolid Phosphate on Survival Outcomes and Suppression of Production of Staphylococcal Toxins in a Rabbit Model of Methicillin-Resistant Staphylococcus aureus Necrotizing Pneumonia

The protective efficacy of tedizolid phosphate, a novel oxazolidinone that potently inhibits bacterial protein synthesis, was compared to those of linezolid, vancomycin, and saline in a rabbit model of Staphylococcus aureus necrotizing pneumonia. Tedizolid phosphate was administered to rabbits at 6...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Antimicrob Agents Chemother
Main Authors: Le, Vien T. M., Le, Hoan N., Pinheiro, Marcos Gabriel, Hahn, Kenneth J., Dinh, Mary L., Larson, Kajal B., Flanagan, Shawn D., Badiou, Cedric, Lina, Gerard, Tkaczyk, Christine, Sellman, Bret R., Diep, Binh An
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2017
Teme:
Experimental Therapeutics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5365717/
https://ncbi.nlm.nih.gov/pubmed/28137816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02734-16
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