Effects of Tedizolid Phosphate on Survival Outcomes and Suppression of Production of Staphylococcal Toxins in a Rabbit Model of Methicillin-Resistant Staphylococcus aureus Necrotizing Pneumonia

The protective efficacy of tedizolid phosphate, a novel oxazolidinone that potently inhibits bacterial protein synthesis, was compared to those of linezolid, vancomycin, and saline in a rabbit model of Staphylococcus aureus necrotizing pneumonia. Tedizolid phosphate was administered to rabbits at 6...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Antimicrob Agents Chemother
Päätekijät: Le, Vien T. M., Le, Hoan N., Pinheiro, Marcos Gabriel, Hahn, Kenneth J., Dinh, Mary L., Larson, Kajal B., Flanagan, Shawn D., Badiou, Cedric, Lina, Gerard, Tkaczyk, Christine, Sellman, Bret R., Diep, Binh An
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2017
Aiheet:
Experimental Therapeutics
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5365717/
https://ncbi.nlm.nih.gov/pubmed/28137816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02734-16
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