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An efficient and precise method for generating knockout cell lines based on CRISPR‐Cas9 system

Although the efficiency and versatility of CRISPR‐Cas9 system has been greatly improved over conventional genome editing methods such as zinc finger or TALEN, it is still time‐consuming and labor‐intensive for screening knockout/knock‐in cell clones due to differences of the targeted location or eff...

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Detaylı Bibliyografya
Yayımlandı:Eng Life Sci
Asıl Yazarlar: Lu, Xibin, Guo, Yuhan, Gu, Shu, Tan, Deng, Cheng, Baoyun, Li, Zhoufang, Huang, Wei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7708952/
https://ncbi.nlm.nih.gov/pubmed/33304232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/elsc.202000032
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