CRISPR/Cas9 Methodology for the Generation of Knockout Deletions in Caenorhabditis elegans

The Caenorhabditis elegans Gene Knockout Consortium is tasked with obtaining null mutations in each of the more than 20,000 open reading frames (ORFs) of this organism. To date, approximately 15,000 ORFs have associated putative null alleles. As there has been substantial success in using CRISPR/Cas...

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Detalhes bibliográficos
Publicado no:G3 (Bethesda)
Main Authors: Au, Vinci, Li-Leger, Erica, Raymant, Greta, Flibotte, Stephane, Chen, George, Martin, Kiana, Fernando, Lisa, Doell, Claudia, Rosell, Federico I., Wang, Su, Edgley, Mark L., Rougvie, Ann E., Hutter, Harald, Moerman, Donald G.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2018
Assuntos:
Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325907/
https://ncbi.nlm.nih.gov/pubmed/30420468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.118.200778
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