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Mutational and transcriptional landscape of spontaneous gene duplications and deletions in Caenorhabditis elegans

Gene duplication and deletion are pivotal processes shaping the structural and functional repertoire of genomes, with implications for disease, adaptation, and evolution. We employed a mutation accumulation (MA) framework partnered with high-throughput genomics to assess the molecular and transcript...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Konrad, Anke, Flibotte, Stephane, Taylor, Jon, Waterston, Robert H., Moerman, Donald G., Bergthorsson, Ulfar, Katju, Vaishali
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048555/
https://ncbi.nlm.nih.gov/pubmed/29941601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1801930115
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