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Mutational and transcriptional landscape of spontaneous gene duplications and deletions in Caenorhabditis elegans

Gene duplication and deletion are pivotal processes shaping the structural and functional repertoire of genomes, with implications for disease, adaptation, and evolution. We employed a mutation accumulation (MA) framework partnered with high-throughput genomics to assess the molecular and transcript...

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Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Konrad, Anke, Flibotte, Stephane, Taylor, Jon, Waterston, Robert H., Moerman, Donald G., Bergthorsson, Ulfar, Katju, Vaishali
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048555/
https://ncbi.nlm.nih.gov/pubmed/29941601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1801930115
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