Mutational and transcriptional landscape of spontaneous gene duplications and deletions in Caenorhabditis elegans

Gene duplication and deletion are pivotal processes shaping the structural and functional repertoire of genomes, with implications for disease, adaptation, and evolution. We employed a mutation accumulation (MA) framework partnered with high-throughput genomics to assess the molecular and transcript...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Konrad, Anke, Flibotte, Stephane, Taylor, Jon, Waterston, Robert H., Moerman, Donald G., Bergthorsson, Ulfar, Katju, Vaishali
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2018
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048555/
https://ncbi.nlm.nih.gov/pubmed/29941601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1801930115
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