CRISPR/Cas9 Methodology for the Generation of Knockout Deletions in Caenorhabditis elegans

The Caenorhabditis elegans Gene Knockout Consortium is tasked with obtaining null mutations in each of the more than 20,000 open reading frames (ORFs) of this organism. To date, approximately 15,000 ORFs have associated putative null alleles. As there has been substantial success in using CRISPR/Cas...

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Vydáno v:G3 (Bethesda)
Hlavní autoři: Au, Vinci, Li-Leger, Erica, Raymant, Greta, Flibotte, Stephane, Chen, George, Martin, Kiana, Fernando, Lisa, Doell, Claudia, Rosell, Federico I., Wang, Su, Edgley, Mark L., Rougvie, Ann E., Hutter, Harald, Moerman, Donald G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Genetics Society of America 2018
Témata:
Investigations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325907/
https://ncbi.nlm.nih.gov/pubmed/30420468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.118.200778
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