CRISPR/Cas9 Methodology for the Generation of Knockout Deletions in Caenorhabditis elegans

The Caenorhabditis elegans Gene Knockout Consortium is tasked with obtaining null mutations in each of the more than 20,000 open reading frames (ORFs) of this organism. To date, approximately 15,000 ORFs have associated putative null alleles. As there has been substantial success in using CRISPR/Cas...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:G3 (Bethesda)
Main Authors: Au, Vinci, Li-Leger, Erica, Raymant, Greta, Flibotte, Stephane, Chen, George, Martin, Kiana, Fernando, Lisa, Doell, Claudia, Rosell, Federico I., Wang, Su, Edgley, Mark L., Rougvie, Ann E., Hutter, Harald, Moerman, Donald G.
Format: Artigo
Jezik:Inglês
Izdano: Genetics Society of America 2018
Teme:
Investigations
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325907/
https://ncbi.nlm.nih.gov/pubmed/30420468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.118.200778
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