Efficient and specific generation of knockout mice using Campylobacter jejuni CRISPR/Cas9 system

The Streptococcus pyogenes CRISPR/Cas9 (SpCas9) system is now widely utilized to generate genome engineered mice; however, some studies raised issues related to off-target mutations with this system. Herein, we utilized the Campylobacter jejuni Cas9 (CjCas9) system to generate knockout mice. We desi...

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書目詳細資料
發表在:Biochem Biophys Rep
Main Authors: Lee, Jae Young, Jang, Yoo Jin, Bae, Ji Hyun, Lee, Yoon Hoo, Bae, Hee Sook, Kim, Seokjoong, Park, Sin-Gi, Koo, Ok Jae, Yeom, Su Cheong
格式: Artigo
語言:Inglês
出版: Elsevier 2020
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SHORT COMMUNICATION
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7118303/
https://ncbi.nlm.nih.gov/pubmed/32258440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2020.100752
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