D614G Spike Mutation Increases SARS CoV-2 Susceptibility to Neutralization

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein acquired a D614G mutation early in the pandemic that confers greater infectivity and is now the globally dominant form. To determine whether D614G might also mediate neutralization escape that could compromise vaccine eff...

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Publicat a:Cell Host Microbe
Autors principals: Weissman, Drew, Alameh, Mohamad-Gabriel, de Silva, Thushan, Collini, Paul, Hornsby, Hailey, Brown, Rebecca, LaBranche, Celia C., Edwards, Robert J., Sutherland, Laura, Santra, Sampa, Mansouri, Katayoun, Gobeil, Sophie, McDanal, Charlene, Pardi, Norbert, Hengartner, Nick, Lin, Paulo J.C., Tam, Ying, Shaw, Pamela A., Lewis, Mark G., Boesler, Carsten, Şahin, Uğur, Acharya, Priyamvada, Haynes, Barton F., Korber, Bette, Montefiori, David C.
Format: Artigo
Idioma:Inglês
Publicat: Published by Elsevier Inc. 2021
Matèries:
Short Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7707640/
https://ncbi.nlm.nih.gov/pubmed/33306985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2020.11.012
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